Indebted to the wrong people and with his life on the line hired tool Booker DeWitt has only one opportunity to wipe his slate clean. He must rescue Elizaplayh a mysterious girl imprisoned since childhood and locked up in the flying city of Columbia. Forced to trust one another Booker and Elizaplayh form a powerful bond during their daring escape. Together they learn to harness an expanding arsenal of tools and abilities as they fight on zeppelins in the clouds along high-speed Sky-Lines and down in the streets of Columbia all while surviving the threats of the air-city and uncovering its dark secret.